A key component of the Health Delivery Systems Center for Diabetes Translational Research (HDS-CDTR) is its Pilot and Feasibility Program. This program fosters and supports pilot projects in diabetes translational research led by promising early stage investigators at the Center’s sites. The specific aims of this Program are: 1. To support two Pilot and Feasibility studies in each year of the HDS-CDTR renewal; 2. To conduct peer review of Pilot and Feasibility award applications on an annual basis, using the following criteria: overall impact; relevance to diabetes translational research; the promise for leading to an R-level grant submission; relevance to the Center’s Translational Research Cores; and support of the health care delivery system in which they are initiated; 3. To leverage the Pilot and Feasibility awards as a mechanism to support junior investigators in developing robust careers in translational research in diabetes and diabetes prevention.



Title of Project: Implementation and Effectiveness of Community Diabetes Prevention Programs in the United States 
Project Principal Investigator:Ilya Golovaty, MD, Research Fellow (Affiliate Faculty)

Project Summary:  
This objective of this proposal is to examine implementation and public health impact of community Diabetes Prevention Programs (DPP). We will use the Reach, Effectiveness, Adaptation, Implementation, and Maintenance (RE-AIM) framework to assess DPP uptake in a large cohort of "high risk" adults referred to community DPP across multiple payers and states and to examine public health impact of the DPP program in community practice.

Title of Project: Investigation of Prevalence of and Barriers to Achieving Optimal Glycemic Control among Women with Gestational Diabetes 
Project Principal Investigator:Yeyi Zhu, PhD, Staff Scientist, Kaiser Permanente Northern California (Affiliate Faculty)

Project Summary:  
This pilot project aims to: (1) create a merged database linking glycemic control data and GDM registry data and describe the central tendency characteristics (mean, SD, range, etc.) and frequency of self-monitored capillary glucose data; (2) Compare the percentage of women with GDM achieving optimal glycemic control defined as ≥80% of all capillary glucose measurements meeting target goals (<5.3 mmol/L for fasting and <7.8 mmol/L 1-hour postprandial) by GDM treatment modalities; (3) . Assess the utilization rate of supplemental GDM care resources from the KPNC RPSC (indicated by the number of received/number of scheduled counseling telephone calls) and patient adherence to glucose self-monitoring (total number and frequency of self-monitored glucose measurements) in relation to glycemic control, among women with GDM identified in the KPNC Glucose Tolerance and GDM Registry between 2008 and 2018.


Title of Project: Tablet Research to Improve Understanding of Medications for People’s Health (TRIUMPH)
Project Principal Investigator: Courtney Lyles, PhD, Assistant Professor, UCSF (Affiliate Faculty)

Project Summary:
This proposal aims to design a tablet application in the waiting room to improve patient-provider communication for complex patients with diabetes on many medications. This is of utmost importance since there are many significant barriers to adherence and safety among patients taking multiple chronic medications, coupled with limited amount of time during visits with providers to discuss all concerns and issues.  Moreover, patients served in safety net healthcare settings have the most to gain from literacy- and language-appropriate technologies that facilitate communication. We will design a simple-to-use tablet application that will educate patients about the importance of bringing up medication concerns at the beginning of the visit and collect current medication concerns that can be shared in real-time with providers during in-person visits.  This will be developed with both patient and provider input in English and Spanish.

Title of Project: Pilot Study of eHealth Medication Messages for Latino Patients and Their Families 
Project Principal Investigator: Veronica Yank, MD, Assistant Professor in Residence, UCSF (Affiliate Faculty)

Project Summary:  
This project will improve the health of Latino adults with diabetes by translating and culturally adapting electronic health messages promoting effective medications that are indicated for specific patients but are not yet prescribed. Existing English-language electronic ( “eHealth) messages targeting non-Latino patients require adaptation for Latino patients and their families. We will adapt existing eHealth messages to be bilingual and culturally-appropriate and then pilot test them in focus groups and semi-structured interviews with patients, family members, and primary care providers for their acceptability and potential for impact.

For more information on completed projects, please visit: Pilot and Feasibility_Completed.pdf